Programmatic interfaces to engage with the Microsoft Security Response Center (MSRC).
Microsoft Security Response Center (MSRC) API is a free Security API that requires no API key, is served over HTTPS and has unconfirmed CORS support.
Notify Microsoft about an issue of abuse or privacy originating from a Microsoft-hosted property, or infringement of your copyright or trademark.
Details from msrc.microsoft.com.

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Reputation of IPs, domains, URLs and file hashes from aggregated threat feeds, plus CVE lookups
The Microsoft Security Response Center (MSRC) API is provided by Microsoft security reporting portal (msrc.microsoft.com). Notify Microsoft about an issue of abuse or privacy originating from a Microsoft-hosted property, or infringement of your copyright or trademark.
Yes. The Microsoft Security Response Center (MSRC) API is listed in the Security category of the public-apis directory, which only includes APIs that are free or have a free tier. Check its documentation for rate limits and paid plans.
No. The Microsoft Security Response Center (MSRC) API requires no authentication, so you can start making requests without signing up.
CORS support for the Microsoft Security Response Center (MSRC) API is unknown. Test a request from the browser, and fall back to a server-side call if it is blocked.
Yes. The Microsoft Security Response Center (MSRC) API is served over HTTPS, so it's safe to use in production.